Meropenem 500 Mg Every 6 Hours

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Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in ad…

    https://www.ncbi.nlm.nih.gov/pubmed/19637944

    Assessment of an alternative meropenem dosing …

      https://pubmed.ncbi.nlm.nih.gov/19637944/
      Conclusion: The alternative meropenem dosage of 500 mg every 6 hours yielded similar patient outcomes, including time to defervescence, need for additional antibiotics, duration of therapy, and mortality, when compared with the traditional meropenem …

    Meropenem: Package Insert / Prescribing Information - Drugs.com

      https://www.drugs.com/pro/meropenem.html

      FOR INTRAVENOUS USE ONLY - Food and Drug …

        https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050706s022lbl.pdf
        dose. No accumulation of meropenem in plasma or urine was observed with regimens using 500 mg administered every 8 hours or 1 g administered every 6 hours in volunteers …

      Steady-state pharmacokinetics and pharmacodynamics …

        https://pubmed.ncbi.nlm.nih.gov/18503396/
        Setting: One tertiary care medical center and one community hospital. Patients: Twenty adult patients (12 men, 8 women) with suspected or documented bacterial infections …

      Evaluation of Meropenem Extended Versus Intermittent …

        https://pubmed.ncbi.nlm.nih.gov/29954243/
        In this retrospective study, we compared intensive care unit (ICU) mortality and clinical response in patients who received meropenem for ≥72 hours administered per EIM …

      THE NEBRASKA MEDICAL CENTER …

        https://www.unmc.edu/intmed/_documents/id/asp/news/meropenem_protocol-detail.pdf
        o Patients received meropenem 500mg every 6 (creatinine clearance [CrCl] > 60 ml/min), 8 (CrCl 40-60 ml/min), or 12 (CrCl 10-39 ml/min) hours Results: Cumulative Fraction of …

      Anti-Infective Dosing Protocols: Meropenem, …

        https://www.nebraskamed.com/sites/default/files/documents/for-providers/asp/Dosing-Protocol-RPeducation.pdf
        –Prescriber orders meropenem 2g q8hr in a patient w/ sepsis of unknown source. Dose should be automatically adjusted by the pharmacist to 500mg q6hr. –Prescriber orders …

      Population Pharmacokinetics and Pharmacodynamics of …

        https://pubmed.ncbi.nlm.nih.gov/27530916/
        Only 500 mg q8h, infused over 0.5 hour, did not achieve >90% PTA at 54% fT>MIC in nonobese and morbidly obese patients. At 100% fT>MIC, 1 g q6h and 2 g q8h, infused …

      Pharmacokinetics and pharmacodynamics of …

        https://pubmed.ncbi.nlm.nih.gov/15598967/
        Based on this relationship, dosing with intravenous meropenem 500 mg every 6 hours is predicted to be comparable to the currently recommended 1 g every 8 hours for serious …

      Meropenem 500 Mg Every 6 Hours - hoursfinder.com

        https://hoursfinder.com/m-hours/meropenem-500-mg-every-6-hours.html
        Two open-label studies compared meropenem 500 mg every 8 hours (total evaluable n=146) with imipenem/cilastatin 500mg every 6 hours (n=147). Clinical efficacy rates in …

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