Paclitaxel Over 24 Hours

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paclitaxel injection, USP Dosage and Administration

    https://www.pfizermedicalinformation.com/en-us/paclitaxel/dosage-admin
    Paclitaxel administered intravenously over 24 hours at a dose of 135 mg/m 2 followed by cisplatin at a dose of 75 mg/m 2. 2) In patients previously treated with chemotherapy for carcinoma of the ovary, paclitaxel has been used at several doses and schedules; …

Paclitaxel Dosage Guide + Max Dose, Adjustments

    https://www.drugs.com/dosage/paclitaxel.html
    Usual Adult Dose for Ovarian Cancer. For previously untreated patients with cancer of the ovary: 175 mg/m2 IV over 3 hours followed by cisplatin 75 mg/m2 IV every …

Paclitaxel - StatPearls - NCBI Bookshelf

    https://www.ncbi.nlm.nih.gov/books/NBK536917/
    Paclitaxel is available as an IV formula infused over 3 to 24 hours, depending on the indication or protocol. Certain off …

The Taxanes: Dosing and Scheduling Considerations

    https://www.cancernetwork.com/view/taxanes-dosing-and-scheduling-considerations

    Randomized trial of 3-hour versus 24-hour infusion of …

      https://pubmed.ncbi.nlm.nih.gov/10550134/
      Conclusion: When administered as a continuous 24-hour infusion, high-dose paclitaxel results in a higher tumor response rate than when administered as a 3-hour infusion …

    Paclitaxel by either 1-hour or 24-hour infusion in …

      https://pubmed.ncbi.nlm.nih.gov/9331116/
      Abstract. Our group previously described the activity of carboplatin plus paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) (given as a 24-hour infusion) in 51 …

    Taxol (paclitaxel) injection label - Food and Drug …

      https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl.pdf
      relatively slow efflux of paclitaxel from the peripheral compartment. Pharmacokinetic parameters of paclitaxel following 3- and 24-hour infusions of TAXOL at dose levels of …

    A simplified premedication protocol for one-hour …

      https://pubmed.ncbi.nlm.nih.gov/17072270/
      Background: Many investigations have focused on optimal doses/schedules since regulatory agency approval of paclitaxel (Taxol). Paclitaxel is generally administered at doses of 175 …

    A simplified premedication schedule for 1-hour paclitaxel ...

      https://pubmed.ncbi.nlm.nih.gov/15724950/
      Many investigations have focused on an optimal dosing schedule for paclitaxel since its regulatory approval. Paclitaxel is generally administered at a dose of 175 mg/m2 IV …

    Comparison of 1-hour and 3-hours paclitaxel infusion

      https://pubmed.ncbi.nlm.nih.gov/12566894/
      PAC was administered at 100 mg/m(2) weekly by 1-h (n = 12) or 3-h (n = 13) infusion to patients with advanced cancer (lung, breast, ovarian, cervix, and head and neck). Total …

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