Precedex Use Beyond 24 Hours

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So, why is dexmedetomidine only approved for use for …

    https://theempulse.org/precedex-less-than-24hours/
    Dexmedetomidine is centrally-acting highly-selective a 2-receptor agonist that is approved by the Food and Drug Administration (FDA) for sedation in the ICU for less than 24 …

HIGHLIGHTS OF PRESCRIBING INFORMATION ...

    https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/021038s035lbl.pdf
    Precedex is indicated for sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting. Precedex should be administered by …

Precedex: Package Insert / Prescribing Information - Drugs.com

    https://www.drugs.com/pro/precedex.html
    Use of dexmedetomidine beyond 24 hours has been associated with tolerance and tachyphylaxis and a dose-related increase in adverse reactions [see Adverse Reactions (6.1)]. Hyperthermia or …

DEXMEDETOMIDINE HYDROCHLORIDE …

    https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206628s000lbl.pdf
    Use of dexmedetomidine HCl beyond 24 hours has been associated with tolerance (reduction in response after longer duration; a higher dosage of dexmedetomidine HCl is …

HIGHLIGHTS OF PRESCRIBING INFORMATION - Pfizer

    https://labeling.pfizer.com/ShowLabeling.aspx?id=4404
    These trials evaluated the sedative properties of PRECEDEX by comparing the amount of rescue medication (midazolam in one trial and propofol in the second) required to achieve …

Precedex (Dexmedetomidine hydrochloride): Uses, …

    https://www.rxlist.com/precedex-drug.htm
    Use of dexmedetomidine beyond 24 hours has been associated with tolerance and tachyphylaxis and a dose-related increase in adverse reactions [see ADVERSE REACTIONS]. Hyperthermia Or …

DailyMed - PRECEDEX- dexmedetomidine …

    https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=548a88c0-afda-427e-75ac-5af0cfa2224c
    2.1 Administration Instructions - • PRECEDEX dosing should be individualized and titrated to desired clinical response. • PRECEDEX is not indicated for …

PrecedexTM For intravenous use. 1 INDICATIONS …

    https://labeling.pfizer.com/ShowLabeling.aspx?id=12157
    In adult subjects, withdrawal symptoms were not seen after discontinuation of short term infusions of Precedex (<6hours). 5.6Tolerance and Tachyphylaxis Use of …

PRECEDEX- dexmedetomidine hydrochloride injection, …

    https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4419162d-81d4-49bd-96de-1729440bdb74
    Use of dexmedetomidine beyond 24 hours has been associated with tolerance and tachyphylaxis and a dose-related increase in adverse reactions [see …

DEXMEDETOMIDINE (Precedex) | LHSC

    https://www.lhsc.on.ca/critical-care-trauma-centre/dexmedetomidine-precedex
    DEXMEDETOMIDINE (Precedex) | LHSC current COVID-19 measures. Critical Care Trauma Centre LHSC Home Critical Care Trauma Centre DEXMEDETOMIDINE …

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